The 30-share BSE Sensex declined 139.34 points to 35,599.82 and the 50-share NSE Nifty slipped 48.70 points to 10,808.
Benchmark indices ended lower on Thursday as investors looked cautious ahead of ECB policy rate decision due later in the day after the US Federal Reserve raised interest rate by 25 basis points.
Rate hike in the Federal Reserve System in the US and a widening current account deficit closer home snapped a 3-day winning run in the equity markets on Thursday.
TCS, Infosys, SBI, ICICI Bank, Axis Bank, Titan Company, Vedanta and L&T were under pressure while Lupin, Sun Pharma, Cipla and Coal India gained.
The nifty Midcap index ended flat NSE Nifty managed to stay above 10,800-mark despite losing half a per cent.
Both IT and PSU Bank sub-indices lost 1.5 per cent during the day’s trade. Pharma which gained 2 per cent was the only sector to finish in the green.
Strides Shasun, Divis Labs, Wockhardt, Alembic Pharma, Torrent Pharma, Westlife Development, Jubilant Foodworks, KPIT Tech, NIIT Tech, MMTC, Dredging Corporation, Jubilant Industries, ITDC, VIP Industries, Venkys, Tata Global, Ashok Leyland gained up to 20 per cent.
Mindtree, Sun TV, M&M Financial and Manappuram Finance were under pressure.
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